1 Features
• Supports ECG and respiration impedance
measurement; configurable as 2-channel ECG or
1-channel ECG + 1-channel respiration
• Can be used in IEC 60601-2-47:2012/(R)2016 and
IEC 60601-2-27:2011(R)2016 compliant systems
• 222 μA/channel while operating as 2-channel ECG
• Integrated Pace pulse detection on 1 channel
• Supports a 3-lead ECG, extendable to 5 leads or
higher by operating two or more AFEs in parallel
• PPG signal chain for SpO2, Heart rate and PTT
• ECG signal chain:
– Single channel ECG acquisition up to 2.048
kHz
– 2 channel ECG acquisition up to 1.36 kHz/
channel
– RLD output to set body bias through third
electrode
– Programmable INA gain from approximately 2
to 12
– >1 GΩ input impedance, CMRR > 100 dB
– Input noise (0.5-150 Hz): 13 μVpp at INA gain
of 3; 5 μVpp at INA gain of 12
– Integrated 370 Hz anti-aliasing low pass filter
– Mode for continuous lead on/off detection
– Mode for lead impedance measurement
• Bio-Z signal chain:
– Measurement of Bio-impedance over excitation
frequency from 30 kHz to 100 kHz
– Sine wave or square wave excitation
– Respiration impedance measurement: 45 mΩ-
pp noise on a baseline impedance of 2 kΩ
• Dual channel ECG channel:
– Bio-Z receiver configurable as a 2nd ECG
channel
• PPG Signal Chain
– Supports acquisition of up to 24 PPG signals
– Flexible allocation of 4 LED, 4 PD in each
phase
– 8-Bit LED Current control up to 250 mA
– Low noise current DAC at input to cancel DC
– Trans-impedance Gain: 3.7 kΩ to 1 MΩ
– Filter to reduce sensor’s optical noise
bandwidth
• External clock and internal oscillator modes
• FIFO with 128-sample Depth, 24-bit word
• SPITM, I2C interfaces: Selectable by pin
• 2.6-mm × 2.6-mm DSBGA, 0.4-mm Pitch
• Supplies: Rx:1.7-1.9 V, IO:1.7-1.9 V, Tx: 3.0-5.5 V

2 Applications
• Wireless patches for in-patient and out-patient
monitoring
• Event monitors for arrhythmia detection
• Hand-held ECG monitor
• Portable multi-lead ECG
• Patient vital sign monitoring: holter, event, stress
and telemedicine
• SpO2 & Heart rate, and PTT-based blood pressure
through synchronized ECG, PPG

3 Description
The AFE4960P supports synchronized signal
acquisition of ECG, PPG and bio-impedance signals.
A PPG signal chain comprises of a current driver for
LEDs and a receiver that senses the signal from PDs.
The AFE can be configured as either a 2-channel
ECG receiver or as a 1-channel ECG receiver and
a Respiration impedance channel. The AFE signal
chains can interface in a flexible manner to up to 4
electrodes. The AFE has AC and DC Lead biasing
and lead on/off detection. Pacemaker pulse detection
is supported on one channel. All the signal chain
outputs are converted by a single ADC in well-defined
time slots and stored as 24-bit words in a 128-sample
FIFO which can be read out using a SPI or an I2C
interface. The AFE4960P can be used to realize a
3-lead ECG system along with SpO2.